2000+ purchased in the last 30 days

NIA 10 Niacinamide Serum

4.6
Rated 4.6 out of 5 stars
4.6 Stars (1,194 Reviews)
(Based on 1194 reviews)
4.6
Rated 4.6 out of 5 stars
4.6 Stars (1,194 Reviews)
(Based on 1194 reviews)

A calming serum designed to help strengthen your skin's defenses while reducing redness and irritation, making it perfect booster for those with sensitive, inflamed, dry, or acne-prone skin.

1.0 fl oz / 30 ml

Key Benefits:
  • Calms redness
  • Strengthens the skin barrier
Key Ingredients:
  • Niacinamide
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If you're not 100% happy, return the products within 100 days for a full refund. We'll even cover the return shipping. It's our commitment to ensure that you're completely satisfied with your Maelove journey.

Obsessively Formulated

Nia 10 harnesses the power of 10% niacinamide (vitamin B3) to effectively soothe sensitive skin and alleviate redness by strengthening the skin barrier and protecting against environmental stressors.

Beyond its calming effects, niacinamide also regulates sebum production, helping to reduce acne breakouts and the look of enlarged pores. Its anti-inflammatory properties further reduce inflammation and hyperpigmentation, promoting clearer, healthier-looking skin with improved texture and tone.

Combined with the astringent properties of zinc PCA, fomes officinalis mushroom extract, and witch hazel water, alongside soothing aloe and white tea, this booster serum helps keep sensitive, inflamed, or acne-prone skin under control.

10% niacinamide (vitamin B3) strengthens the skin barrier and improves overall skin health
  • Enhances the skin's natural barrier function, helping to retain moisture and protect against environmental stressors
  • Soothes irritation, calm redness, and improve uneven skin tone
  • Stimulates collagen and elastin production, which helps maintain skin elasticity and firmness
Regulates sebum production to help with breakouts and large pores
  • Balances oil production, minimizing excess oiliness and reducing the appearance of enlarged pores
  • A supporting cast of naturally astringent ingredients further help keep pores clear
  • Promotes skin cell renewal, leading to smoother, more even skin texture

Use AM and/or PM. Apply a thin layer of serum to the face, neck, and chest. Massage product in until it is fully absorbed. Follow with a gentle moisturizer to lock in the serum.

Layer your products from thinnest to thickest in texture, waiting a full minute between each product.

See our How to Layer guide for tips on layering multiple Maelove products.

Key Ingredients

10% Niacinamide (Vitamin B3)



Supporting Ingredients

Zinc PCA, White Tea, Aloe, Fomes Officinalis (Mushroom), Witch Hazel


All Maelove products are safe for sensitive skin, made in the US, vegan, cruelty-free, non-comedogenic, gluten-free, and free of parabens, phthalates, dyes, and artificial fragrances. We don't use ingredients that are banned in the EU or in the USA.


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Customer Reviews

4.6
Rated 4.6 out of 5 stars
Based on 1,194 reviews
Total 5 star reviews: 967 Total 4 star reviews: 96 Total 3 star reviews: 55 Total 2 star reviews: 29 Total 1 star reviews: 47
1,194 reviews
  • KD
    Kassandra D.
    Verified Buyer
    I recommend this product
    What are your skin concerns? Acne and blemishes, Redness and sensitivity, Dryness
    How old are you? 25-34
    What is your skin type? Sensitive
    Product Standouts Dramatic Results, Hydrating, Great Ingredients, Healing, Gentle
    Rated 5 out of 5 stars
    3 months ago
    Amazing Niacin Serum!

    I’ve been using this items for years and it’s been my holy grail!! It reduces my redness tremendously and keeps my face hydrated and supple! Love, love, love!!

  • AH
    Anna H.
    Verified Buyer
    I recommend this product
    What are your skin concerns? Acne and blemishes, Redness and sensitivity
    How old are you? 25-34
    What is your skin type? Sensitive
    Product Standouts Healing, Hydrating, Dramatic Results
    Rated 5 out of 5 stars
    7 months ago
    Love this product!

    I have always been hesitant to use niacinamide as I get scared it will break me out but I use this product both AM and PM now and it's helped my skin so much with acne pigmentation. I have extremely sensitive skin and I have had no issues! It's lightweight and I store it in my fridge.

  • LA
    Loren A.
    Verified Buyer
    I recommend this product
    What are your skin concerns? Redness and sensitivity, Dryness, Fine lines and wrinkles, Sun Damage
    How old are you? 45-54
    What is your skin type? Dry
    Product Standouts Dramatic Results, Easy To Use, Gentle, Great Ingredients
    Rated 5 out of 5 stars
    9 months ago
    This works!

    I love how easily this goes on and how well it absorbs. I use this at night and in the morning and have seen a huge decrease in redness.

  • DF
    Denise F.
    Flag of United States
    Verified Buyer
    I recommend this product
    What are your skin concerns? Redness and sensitivity, Dryness
    How old are you? 55+
    What is your skin type? Combination
    Rated 5 out of 5 stars
    1 year ago
    NIA 10 Walks the Talk

    My experience with Maelove products has been excellent! I use a number of their ingredients, and the NIA 10, was the 3rd product that I purchased. I developed skin cancer recently, and have a number of pre-cancer marks on my face. I've had Mohs surgery as well but the patches of red are itchy, dry and difficult to control. The NIA10 plus the Hydrator have calmed the redness, peeling (dryness) affect and appearance of these spots. I have used Tretinoin (per my Dermatologist), but it was making my face worse. I love all the products that I purchased from Maelove, as they certainly have enhanced my skin appearance. Yes, I can use a good cover up and that works, but it only takes a small amount now compared with using these products. I love the videos and literature that comes with the products. Thank you, Maelove!

  • LF
    Linda F.
    Verified Buyer
    I recommend this product
    What are your skin concerns? Sun Damage, Fine lines and wrinkles, Dark spots, Redness and sensitivity
    How old are you? 55+
    What is your skin type? Normal
    Product Standouts Great texture, Easy To Use, Gentle, Healing, Great Ingredients
    Rated 5 out of 5 stars
    1 week ago
    Calming

    This is probably my favorite of the four Maelove products I use on a daily basis. My redness is what bothers me the most & this truly helps calm it down. I really should purchase a backup bottle in case I run short with my auto renewal. I would hate to run out.

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For the Curious

Niacinamide (vitamin B3) is one of the great tried and true ingredients that seem to have efficacy across many skin conditions. It is scientifically proven to strengthen the natural skin barrier while also being one of the best anti-inflammatory ingredients. It has proven efficacy against redness (Draelos et al. 2005). Clinical studies on efficacy show 5% niacinamide is more effective than 2%, and 10% maximizes efficacy. At the same time, safety studies show that even for up to 20% concentration solutions, there is little to no irritation on skin in patch tests (Gehring 2004, Draelos et al. 2006).

Those with sensitive skin have a weakened skin barrier that allows for environmental irritants to pass through the barrier. This is why those with sensitive skin are prone to inflammation and skin redness as well as contact dermatitis.
Topical application of niacinamide can strengthen the skin barrier because it can penetrate and upregulate important cofactors NAD and NADP (nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate). These cofactors are involved in producing components that make up the skin barrier. Hence, niacinamide can increase production of beneficial proteins (keratin, filaggrin and involucrin) and lipids (ceramides, free fatty acids, and cholesterol) that make up the skin barrier. In clinical studies, Niacinamide has been shown to improve skin barrier function and also increase skin moisture levels in those suffering from rosacea (Draelos et al. 2005) and atopic dermatitis (Soma et al. 2005). Hence, even those with clinically significant impairments in the skin barrier with associated redness can be treated with niacinamide.
To combat inflammation and redness, niacinamide exerts its powerful anti-inflammatory effects via known mechanisms. Niacinamide prevents cytokine-mediated induction of nitric oxide synthase, which leads to a decrease in inflammation, making it useful across multiple inflammatory conditions (Sahin et al. 2021). Niacinamide also inhibits NFkB-transcription of pro-inflammatory mediators, and the expression of interleukins that mediate inflammation (Wohlrahb et al. 2014).

Even at a 2% concentration, niacinamide can reduce sebum and lead to significant decreases in facial shine and oiliness as well as leading to general improvements in skin condition (Draelos et al. 2006). Further, treatment with 4% niacinamide in acne leads to a reduction in inflammatory papules (Gehring 2004). 10% niacinamide maximizes efficacy while at the same time, safety studies show that even for up to 20% concentration solutions, there is little to no irritation on skin in patch tests (Gehring 2004, Draelos et al. 2006).

Niacinamide also has antiretroviral and fungistatic effects (Wohlrahb et al. 2014). One clinical trial found that 4% niacinamide gel was as effective as the antibiotic Clindamycinin in reducing acne lesions and acne severity (Shalita et al. 1995). Hyperpigmentation following inflammation from acne is a common problem for many. The P. acnes bacteria has been implicated in this inflammation by activating interleukin-8 (IL-8) secretion. Niacinamide treatment significantly decreases IL-8 production from P.acnes, as well as downstream effects, in a dose-dependent manner, preventing inflamed papules (Grange et al. 2010). In other words, particularly for those with easily inflamed skin, niacinamide not only helps treat the acne, but the possible post-inflammatory hyperpigmentation that follow inflamed papules.

Niacinamide is such a fantastic anti-aging and skin soothing ingredient, it is often co-formulated across many anti-aging serums and moisturizers. Hence, depending on the content and number of products in your skin routine, you may be getting a good dose of niacinamide without the need of a specialty high concentration niacinamide serum. Nonetheless, high concentration niacinamide may still be a useful addition to your anti-aging and anti-hyperpigmentation regimen if you want to ensure you are maximizing the benefits of niacinamide. In other words, Nia 10 can be a useful adjunct to any anti-aging or anti-hyperpigmentation skin regimen.

Skin aging is associated with a loss of important compounds such as NAD and NADP (nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate) in the skin and these lower levels make cells age and deteriorate faster (Berson et al. 2014). Topical niacinamide increases the levels of NAD and NADP and reverses this trend and increases collagen, making it one of the best anti-aging ingredients (Bissett et al. 2004, Matts et al. 2002).

In aging skin, one study found significant improvement in aging skin with 2.5% niacinamide. A later study replicated this finding with twice the amount and found 5% niacinamide had a greater impact on skin smoothness and wrinkle depth reduction compared to 2% niacinamide in aging skin (Gehring 2004). Another study in aging skin found that 5% niacinamide not only reduced fine lines and wrinkles and improved skin texture, but also reduced skin yellowing and red blotchiness (Bissett et al. 2004). Another follow-up study showed 5% niacinamide also improved elasticity in aging skin (Bissett et al. 2006).
The benefits of niacinamide on hyperpigmentation has been replicated in sun-damaged skin (Kimball et al. 2009), in melasma (Navarrete-Solis et al. 2011), in axillary hyperpigmentation (Castanedo-Cazares et al. 2013), and has been shown to be dose-dependent with 5% niacinamide more effective than 2% niacinamide in reducing hyperpigmentation (Greatens et al. 2005).

Niacinamid plays a role in DNA repair after UV damage in melanocytes. This role is also behind the promise of niacinamide as a chemoprevention agent for melanoma, the most serious type of skin cancer (Thompson et al. 2014). Though preventing skin cancer may be the more important attribute of this mechanism, there is also another benefit. As DNA becomes methylated in response to UV, the methylated DNA also induces pro-inflammatory and pro-melanogenic genes. In one study, niacinamide reduced methylated DNA and melasma based hyperpigmentation after 8 weeks compared to placebo (Campuzana et al. 2019). In addition to its role in DNA repair, niacinamide can help prevent skin cancer by being photo-protective and protecting against UV-induced immune suppression (Wohlrahb et al. 2014) as well as by having antioxidant properties and protecting against generation of reaction oxygen species in keratinocytes (Zhen et al. 2019). Since niacinamide protects against the effects of UV rays (and UV-induced photo-suppression), like Vitamin C, niacinamide can be used to help bolster your skin’s defenses during the day (Wohlrahb et al. 2014). While Vitamin C and E are the main antioxidants that fight against UV damage in your skin, and Glow Maker is still our primary recommendation for this purpose, if your skin can not tolerate these serums which are acidic (pH < 3.5) due to irritation, then NIA 10 is a good alternative
It can also help protect against UV-damage making it a good alternative for those with sensitive skin who can not tolerate acidic vitamin C serums.

Yes you can. Maelove serums are all carefully formulated to allow every serum to be used together in a layering fashion. We’ve done all the thinking so you don’t have to! For an extended writeup on this topic, please consult the Maelove science blog post.

Yes you can. The actives in Nia 10 including niacinamide, witch hazel, aloe, and fomes officinalis (Mushroom) extract are all considered generally safe to use topically during pregnancy and lactation. However, it is always advisable to check with your doctor regarding skin care products and ingredients and follow their protocol.

Draelos ZD, Ertel K, Berge C (2005). “Niacinamide-containing Facial Moisturizer Improves Skin Barrier and Benefits Subjects with Rosacea.” Cutis 76:135-141

Gehring W (2004). “Nicotinic acid/ niacinamide and the skin.” Journal of Cosmetic Dermatology 3:88-93.

Sahin K, Kucuk O, Orhan C, Tuzcu M, Durmus AS, Ozercan IH, Sahin N, Juturu V (2021). “Niacinamide and undenatured type II collagen modulates the inflammatory response in rats with monoiodoacetate-induced osteoarthritis.” Scientific Reports 11:14724. Doi:10.1038/s41598-021-94142-3.

Soma Y, Kashima M, Imaizumi A, Takahama H, Kawakami T, Mizoguchi M (2005). “Moisturizing effects of topical nicotinamide on atopic dry skin.” Int J Dermatol 44:197–202.

Wohlrab J, Kreft D (2014). “Niacinamide-Mechanisms of Action and Its Topical Use in Dermatology.” Skin Pharmacol Physiol. 27:311-315.

Draelos ZD, Matsubara A, Smiles K (2006). “The effect of 2% niacinamide on facial sebum pro-duction.” J Cosmet Laser Ther 8:96–101

Gehring W (2004). “Nicotinic acid/ niacinamide and the skin.” Journal of Cosmetic Dermatology 3:88-93.

Grange PA, Raingeaud J, Calvez V, Dupin N (2010). “Nicotinamide inhibits Propionibacterium acnes-induced IL-8 production in keratinocytes through the NF-kB and MAPK pathways.” J Derm Sci 56(2): P106-112)

Shalita AR, Smith JG, Parish LC, Sofman MS, Chalker DK (1995). “Topical nicotinamide compared with clindamycin gel in the treament of inflammatory acne vulgaris.” International Journal of Dermatology 34(6):434-437.

Wohlrab J, Kreft D (2014). “Niacinamide-Mechanisms of Action and Its Topical Use in Dermatology.” Skin Pharmacol Physiol. 27:311-315.

Bissett DL, Miyamoto K, Sun P, Li J, Berge CA (2004). “Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin.” International Journal of Cosmetic Science. 26: 231-238.

Bissett DL, Oblong JE, Berge CA (2006). “Niacinamide: A B Vitamin that Improves Aging Facial Skin Appearance.” Dermatologic Surgery 31: 860-866

Castanedo-Cazares JP, Larraga-Pinones G, Ehnis-Perez A, Fuentes-Ahumada C, Oros-Ovalle C, Smoller BR, Torres-Alvarez B (2013). “Topical niacinamide 4% and desonide 0.05% for treatment of axillary hyperpigmentation: a randomized, double-blind, placebo-controlled study.” Clinical, Cosmetic and Investigational Dermatology 6:29-36

Gehring W (2004). “Nicotinic acid/ niacinamide and the skin.” Journal of Cosmetic Dermatology 3:88-93.

Greatens A, Hakozaki T, Koshoffer A, Epstein H, Schwemberger S, Babcock G, Bissett D, Takiwaki H, Arase S, Wickett RR, Boissy RE (2005). “Effective inhibition of melanosome transfer to keratinocytes by lectins and niacinamide is reversible.” Experimental Dermatology 14: 498-508.

Kimball AB, Kaczvinsky JR, Li J, Robinson LR, Matts PJ, Berge CA, Miyamoto K, Bissett DL (2009). “Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial.” British Journal of Dermatology 162: 435-441

Matts PJ, Oblong JE, Bissett DL (2002). “A review of the range of effects of niacinamide in human skin.” IFSCC 5(4): 285-289.

Navarrete-Solis J, Castanedo-Cazares JP, Torres-Alvarez B, Oros-Ovalle C, Fuentes-Ahumada C, Gonzalez FJ, Martinez-Ramirez JD, Moncada B (2011). “A Double-Blind, Randomized Clinical Trial of Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma.” Dermatology Research and Practice. Doi:10.1155/2011/379173

Campuzano-Garcia AE, Torres-Alvarez B, Hernandez-Blanco D, Fuentes-Ahumada C, Cortes-Garcia JD, Castanedo-Cezares JP (2019). “DNA Methyltransferases in Malar Melasma and Their Modification by Sunscreen in Combination with 4% Niacinamide, 0.05% Retinoic Acid, or Placebo.” Biomed Research International. doi:10.1155/2019/9068314

Thompson BC, Surjana D, Halliday GM, Damian D (2014). “Nicotinamide enhances repair of ultraviolet radiation–induced DNA damage in primary melanocytes.” Exp Dermatol 23(7): 509-511. Doi:10.1111/exd.12430

Wohlrab J, Kreft D (2014). “Niacinamide-Mechanisms of Action and Its Topical Use in Dermatology.” Skin Pharmacol Physiol. 27:311-315.

Zhen AX, Piao MJ, Kang KA, Fernando PDSM, Kang HK, Koh YS, Yi JM, Hyun JW (2019). “Niacinamide Protects Skin Cells from Oxidative Stress Inducted by Particulate Matter.” Biomol Ther 27 (6): 562-569

Deep Guide to Niacinamide - How it works and why it should be a part of everyone's skincare routine

This writeup was lead-authored by our senior technical adviser, Sunbin Song, PhD. Sunbin graduated from MIT with a degree in Biology before receiving a doctorate in neuroscience from Georgetown and...